Antwuan was a leader throughout his days at Wheeler High School, playing varsity basketball all four years and boasting a 109-13 record. He scored 1,212 points during his high school career, placing him as the second all-time leading scorer at Wheeler High School. He received the Clone Award, given each year to the student whom his peers would most like to emulate.

After graduating from Wheeler High School in 1998, Antwuan went on to sign a scholarship to play basketball at Florida State University. Dixon would spend the next four years of his career playing a major role in the Seminoles' success on and off the court. He played four years at Florida State University, and he is in the-record books fo·r the most consecutive games played at FSU and named Warrior of the Year in 2002. He went on to graduate with a communications and sociology degree from Florida State. Soon after graduation Dixon would spend time playing professional basketball in the European Basketball Leagues. Today Antwuan Dixon spends his time operating various business ventures, including event productions, night clubs, and multiple restaurants.